YODA's out of action!

[YODA]

Hi MAPers - I've been asked by a few people now to give updates on my current injury status so here's the two emails I sent round recently....

May 7th

Well - it's official. No training or teaching for me for the next 6-8 weeks :-(

I've screwed up the Iliofemoral Ligament and surrounding bits on the outside of my left hip. It's been giving me pain for a while but got much worse this week. The joint capsule is ****ed as a result too - which means the fluid in my joint is not doing its job & my joint is wearing away. Basically I've not to do anything involving hip abduction i.e. opening my legs sideways (ooh err missus). The quack reckons full & proper recovery now rather than a hip replacement in about 5-10 years. He's putting 6-8 weeks as an optimistic minimum :-(

It's a real pain (pun intended) because it only hurts when I do nothing - i.e. sit for more than 5 mins - which is exactly what I'll be doing if I'm not training! Grrrrr!!! The worst is driving - after 10 mins I'm in agony. Looks like profits will be well up for Neurofen inc.

Steve will be running the club for the next month or two so I'm counting on you guys, especially the assistant coaches, to give him your support.

Well - that's the plan anyway. I'm gonna go crazy! Probably be 16 stone by the time I make it back to regular training.

======================

May 9th


Ok - update.

I went to see Physio No.2 today - so that's 1 quack & 2 physios that
all agree that my hip is ****ed :-(

Basically this guy had a good prod & levered my leg into every
imaginable position - and then a few more I hadn't thought of. As is
usually the case the pain of the physio was far more than anything
I've felt with the bad hip - Grrrrr...

Anyway - at one stage he asked me how long ago I fractured my hip. I
replied that I have never fractured my hip. "Yes you have" was his
reply - and it didn't heal very well. Bugger! He reckons that my hip
is slightly out of line which for a "normal person" wouldn't be a
problem. Because I injured my left knee a while back I've changed the
angle that my hip works at to compensate for the dicky knee - and
it's that which has caused my hip to screw up.

He reckons there is no 100% cure for this - only management of the
problem. We're starting with ultrasound & masage to try to break down the scar tissue that's causing the joint to fail. I can see this
getting expensive!

:woo: :woo: :woo: :woo: :woo:

[Levo]

Get well soon my friend.

My back is causing me no end of trouble right now, I'm close to closing my club and packing it in!

Nathan

[YODA]

Sorry to hear that mate - hope things improve :(

[YODA]

Hey Levo - maybe they should throw the two of us into a big sack & shake it up - they may have enough good bits to make ONE healthy body :D

[Brad Ellin]

Dude, I feel for you and right now with you. Please take it easy and listen to the quacks, it's easier to do that for 6-8 weeks than have to stop trtaining permanently.

[morphus]

Hope the time you are away from training flies for and its a quick recovery!:)

[LabanB]

Hi Dave,

Missed the start of this. How/when did you damage your hip?

Bill

[YODA]

I wish I knew Bill - it started giving me pain about a month ago but got much worse whilst driving around Scotland recently.

[Andy Murray]

Anyway - at one stage he asked me how long ago I fractured my hip. I
replied that I have never fractured my hip. "Yes you have" was his
reply - and it didn't heal very well.

Do you have any history of hip trouble, where you may indeed have fractured the hip Dave?

If not, maybe a third opinion?

[YODA]

Nope Andy - he's organising an X-Ray for my next session so that'll shed more light (or rays!) on it :D

[Andy Murray]

You've not had an Xray yet? Shocking!

Listen,
the old hip replacement op is not as bad as it sounds. My mother (EX PE Instructor aged 65) was on her feet in three days (mainly cos she was dying for a fag, but there's motivation in action), after months of suffering.

[darlph]

Hey Yoda, sorry about this whole thing. I hope you come out of it better. Just grit your teeth and consider it as a training exercise, in pain. You will get through this, it just takes time.
A little on the bright side. Bill Superfoot Wallace had a hip replacement a few years ago and he seems to be doing better then ever. Kim, his wife, says he's even better then before. (No, I'm not going there.) He even can throw his golf club further, ha haha Get better and see what the x-rays read. Keep up the humour
Love to you.

[TkdWarrior]

get well sooooooon Yoda,
-TkdWarrior-

[Mo Lung]

You have a woman's hips!

(Get well soon, mate - just couldn't resist a BlackAdder reference! ;) )

[Cain]

I am sure you can whip yourself out of it Yoda ;)

Just jokin' mate, take it easy hope you get up and kickin' @$$ soon :)

|Cain|

[YODA]

Thanks for the kind words MAPers :D

[johndoch]

Sorry to hear that mate.

Get well soon.

[pgm316]

Lets hope the rest and recouperation does the job!

Not being able to do your normal stuff will be the worst bit :(

Get well soon mate!

[Freeform]

Take it easy mate, although I bet he's sitting in his chair, swinging a stick around, trying to develop MA for people who are chairbound! ;)

Get well soon!

[khafra]

Do what the docs say, of course, but you might have someone stick a few needles in you too, or at least try MSM and Glucosamine (although careful with that last, in large amounts it can do worse things to your insulin sensitivity than dextrose/maltodextrin). Good luck getting back to 100%

[craigwarren]

Hey yoda, you could keep teaching your class if you taught them Mr Miyagi style. You know have them build an extension for your house, wax your car that kinda thing. Im sure they'd appreciate such lessons :)

Seriously, hope your ready to start training again asap.

[YODA]

Originally posted by Freeform
Take it easy mate, although I bet he's sitting in his chair, swinging a stick around, trying to develop MA for people who are chairbound! ;)

Get well soon!


LOL! You ain't far off mate :D

[YODA]

Originally posted by khafra
Do what the docs say, of course, but you might have someone stick a few needles in you too, or at least try MSM and Glucosamine (although careful with that last, in large amounts it can do worse things to your insulin sensitivity than dextrose/maltodextrin). Good luck getting back to 100%

Thanks - I already take Glucosamine - 1.5g a day. Any more info on that insulin link? That's set a few alarm bells ringing with experiences I've had over the last year or so!

[YODA]

Originally posted by craigwarren
Hey yoda, you could keep teaching your class if you taught them Mr Miyagi style. You know have them build an extension for your house, wax your car that kinda thing. Im sure they'd appreciate such lessons :)

Seriously, hope your ready to start training again asap.


Hmmmmmmm...... our back fence does need painting and I
do need a bigger run building for our new wabbits :D

[khafra]

Originally posted by YODA


Thanks - I already take Glucosamine - 1.5g a day. Any more info on that insulin link? That's set a few alarm bells ringing with experiences I've had over the last year or so!


Here's some info from the forum at www.anabolicminds.com, with a few articles you could look up on Medline

1.Role of the glucosamine pathway in fat-induced insulin resistance.
J Clin Invest 1997 May 1;99(9):2173-82

2.Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues.
Endocrinology 1997 Jun;138(6):2501-7

3.Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.
Diabetes 1999 Aug;48(8):1562-71

4.Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons.
J Biol Chem 2001 Nov 23;276(47):43748-55

5.Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance.
J Biol Chem 1991 Mar 15;266(8):4706-12

6.Pre-exposure to glucosamine induces insulin resistance of glucose transport and glycogen synthesis in isolated rat skeletal muscles. Study of mechanisms in muscle and in rat-1 fibroblasts overexpressing the human insulin receptor.
Diabetes 1993 Sep;42(9):1333-46

7.Glucosamine levels in people with ischaemic heart disease with and without type II diabetes.
Pol Arch Med Wewn 1998 Nov;100(5):419-25

8.Exercise-stimulated glucose turnover in the rat is impaired by glucosamine infusion.
Diabetes 2001 Jan;50(1):139-42

9.Glucose transport by osmotic shock and vanadate is impaired by glucosamine.
Biochem Biophys Res Commun 2002 Mar 29;292(2):308-11

10.Glucosamine regulation of glucose metabolism in cultured human skeletal muscle cells: divergent effects on glucose transport/phosphorylation and glycogen synthase in non-diabetic and type 2 diabetic subjects.
Endocrinology 1999 Sep;140(9):3971-80

11.Effects of glucosamine infusion on insulin secretion and insulin action in humans.
Diabetes 2000 Jun;49(6):926-35

12.Immunosuppressive effects of glucosamine.
J Biol Chem 2002 Oct 18;277(42):39343-9

13.High glucose and glucosamine induce insulin resistance via different mechanisms in 3T3-L1 adipocytes.
Diabetes 2000 Jun;49(6):981-91

14.Glucosamine-induced insulin resistance in 3T3-L1 adipocytes.
Am J Physiol Endocrinol Metab 2000 Jan;278(1):E103-12

15.The role of glucose metabolites in the activation and translocation of glycogen synthase by insulin in 3T3-L1 adipocytes.
J Biol Chem 1999 Sep 24;274(39):27497-504

16.Hexosamines and nutrient excess induce leptin production and leptin receptor activation in pancreatic islets and clonal beta-cells.
Endocrinology 2001 Oct;142(10):4414-9

17.Endothelin-stimulated glucose uptake: effects of intracellular Ca(2+), cAMP and glucosamine.
Clin Sci (Lond) 2002 Aug;103 Suppl 48:418S-423S

18.Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP.
J Biol Chem 1998 Aug 7;273(32):20658-68

19.Mechanisms of insulin resistance in non-oxidative glucose metabolism: the role of glycogen synthase.
J Basic Clin Physiol Pharmacol 1998;9(2-4):255-79

20.Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress.
J Biol Chem 2001 Aug 17;276(33):31099-104


If your body needs those sulfur-containing compounds that are contained in glusosamine, this supplement may be very beneficial for your joints. However, you can also get sulfer compounds without the risk of side effects from certain foods, including egg yolks, cruciferous vegetables such as broccoli, cauliflower and cabbage, and the trio of garlic, onions, and the spice turmeric. In addition to sulfur, there are many other nutrients just as important for joints; included among them are vitamins B6, B12, folate, pantothenic acid, and the minerals magnesium, manganese and zinc.

Another popular supplement for joint pain relief is chondroitin sulfate. Some helpful compounds found in this substance can also be found in real chicken soup made by boiling the bones and cartilage. Another potentially therapeutic food is a sugar-free gelatin dessert made by adding fruit juice and real fruit instead of water and sugar to plain gelatin.

[khafra]

1.Role of the glucosamine pathway in fat-induced insulin resistance.

J Clin Invest 1997 May 1;99(9):2173-82

Hawkins M, Barzilai N, Liu R, Hu M, Chen W, Rossetti L.

Division of Endocrinology and Diabetes Research and Training Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

To examine whether the hexosamine biosynthetic pathway might play a role in fat-induced insulin resistance, we monitored the effects of prolonged elevations in FFA availability both on skeletal muscle levels of UDP-N-acetyl-hexosamines and on peripheral glucose disposal during 7-h euglycemic-hyperinsulinemic (approximately 500 microU/ml) clamp studies. When the insulin-induced decrease in the plasma FFA levels (to approximately 0.3 mM) was prevented by infusion of a lipid emulsion in 15 conscious rats (plasma FFA approximately 1.4 mM), glucose uptake (5-7 h = 32.5+/-1.7 vs 0-2 h = 45.2+/-2.8 mg/kg per min; P < 0.01) and glycogen synthesis (P < 0.01) were markedly decreased. During lipid infusion, muscle UDP-N-acetyl-glucosamine (UDP-GlcNAc) increased by twofold (to 53.4+/-1.1 at 3 h and to 55.5+/-1.1 nmol/gram at 7 h vs 20.4+/-1.7 at 0 h, P < 0.01) while glucose-6-phosphate (Glc-6-P) levels were increased at 3 h (475+/-49 nmol/gram) and decreased at 7 h (133+/-7 vs 337+/-28 nmol/gram at 0 h, P < 0.01). To discern whether such an increase in the skeletal muscle UDP-GlcNAc concentration could account for the development of insulin resistance, we generated similar increases in muscle UDP-GlcNAc using three alternate experimental approaches. Euglycemic clamps were performed after prolonged hyperglycemia (18 mM, n = 10), or increased availability of either glucosamine (3 micromol/kg per min; n = 10) or uridine (30 micromol/kg per min; n = 4). These conditions all resulted in very similar increases in the skeletal muscle UDP-GlcNAc (to approximately 55 nmol/gram) and markedly impaired glucose uptake and glycogen synthesis. Thus, fat-induced insulin resistance is associated with: (a) decreased skeletal muscle Glc-6-P levels indicating defective transport/phosphorylation of glucose; (b) marked accumulation of the endproducts of the hexosamine biosynthetic pathway preceding the onset of insulin resistance. Most important, the same degree of insulin resistance can be reproduced in the absence of increased FFA availability by a similar increase in skeletal muscle UDP-N-acetyl-hexosamines. In conclusion, our results support the hypothesis that increased FFA availability induces skeletal muscle insulin resistance by increasing the flux of fructose-6-phosphate into the hexosamine pathway.

2.Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance in multiple insulin sensitive tissues.

Endocrinology 1997 Jun;138(6):2501-7

Virkamaki A, Daniels MC, Hamalainen S, Utriainen T, McClain D, Yki-Jarvinen H.

Minerva Foundation Institute for Medical Research, University of Helsinki, Finland. virkamak@helsinki.fi

We determined the effect of infusion of glucosamine (GlcN), which bypasses the rate limiting reaction in the hexosamine pathway, on insulin-stimulated rates of glucose uptake and glycogen synthesis in vivo in rat tissues varying with respect to their glutamine:fructose-6-phosphate amidotransferase (GFA) activity. Three groups of conscious fasted rats received 6-h infusions of either saline (BAS), insulin (18 mU/kg x min) and saline (INS), or insulin and GlcN (30 micromol/ kg x min, GLCN). [3-(3)H]glucose was infused to trace whole body glucose kinetics and glycogen synthesis, and rates of tissue glucose uptake were determined using a bolus injection of [1-(14)C]2-deoxyglucose at 315 min. GlcN decreased insulin-stimulated glucose uptake (315-360 min) by 49% (P < 0.001) at the level of the whole body, and by 31-53% (P < 0.05 or less) in the heart, epididymal fat, submandibular gland and in soleus, abdominis and gastrocnemius muscles. GlcN completely abolished glycogen synthesis in the liver. GlcN decreased insulin-stimulated glucose uptake similarly in the submandibular gland (1.3 +/- 0.2 vs. 2.0 +/- 0.3 nmol/mg protein x min, GLCN vs. INS, P < 0.05) and gastrocnemius muscle (1.4 +/- 0.3 vs. 3.1 +/- 0.5 nmol/mg protein x min), although the activity of the hexosamine pathway, as judged from basal GFA activity, was 10-fold higher in the submandibular gland (286 +/- 35 pmol/mg protein x min) than in gastrocnemius muscle (27 +/- 3 pmol/mg protein x min, P < 0.001). These data raise the possibility that overactivity of the hexosamine pathway may contribute to glucose toxicity not only in skeletal muscle but also in other insulin sensitive tissues. They also imply that the magnitude of insulin resistance induced between tissues is determined by factors other than GFA.

(I'll just post the full abstract of those first two, unless someone asks for more)

[little lion]

Dear yoda,
sorry to hear about your injury my friend,have you thought about traditional chinese medicine to heal it . My sifu is a traidional bone and muscle specialist,and has been known to fix all kind of injuries in a relitively short space of time, he fixed a guys snapped knee in a few weeks, and he has just fixed my ankle which was really messed up with tendon and ligament damage, it had been causing my bother for months and he fixed it in a few days. You may never have thought of this type of treatment, but it may be wise to explore all options to heal you. If you want to look into it just give me a shout my friend.
best regards
dave

[YODA]

Thanks Dave - I've some irons in that fire :D I've been speaking to my mate at work who's been teaching Tai Chi for the last 15 years - he knows a few people that may be able to help.

[KickChick]

...let me just add to the the rest of the wishes for an early and good-as-new recovery for you!http://216.40.249.192/s/contrib/edoom/sick.gif

Besides ours ..... get plenty of professional opinions!!!

[Cudgel]

I feel for you becasue several months ago our head dude suffered what amounted to a stroke and was told that he would never fight again. wel several months of physical therapy and fighitng and now I fear for my life again. He can swing a mean stick. nad thius all while having little mobilty in his legs and with his left hand.


may you heal quickly and be better than ever.

[r4bid]

I have a friend who developed a sort of crutch-fu, fighting with crutches. Its pretty cool stuff but he stopped doing it once his legs healed.

[Cougar_v203]

hehehe crutch fu hehehe...sorry i couldn't resist ;)

[Jack]

Originally posted by Cougar_v203
hehehe crutch fu hehehe...sorry i couldn't resist ;)

I started learning crutch fu for about a week after I hurt me ankle, the kicking possibilities with four effective legs are impressive. :D

Dave, I'm very sorry to hear this mate. Will you be kept at home or will you be going to work? Because if you're staying at home, its a great chance to spend time with family and to follow other, less physical, activities!

Take care friend.

[Freeform]

Just keep away from the pizza mate. I was out for 3 months once and really had to watch what I was eating cause I wasn't active. Make sure ya don't blimp! ;)

[YODA]

Nah! I'm lardy enough as it is - I haven't been this outa shape for years - I've got my motivated head on - I'm gonna turn this obstacle into a stepping stone!

Everything happens for a reason - and I'm beginning to why this is now.

[Jack]

"I'm going to turn this obstacle into a stepping stone."

You're like a modern day Sun Tzu. :)

[Brad Ellin]

"Everything happens for a reason - and I'm beginning to why this is now."

Truer words never spoken Yoda. I have the same ... not problem, but affliction?... Worse physical shape I have been in, in years. But then again, i have never had so many problems hit me like this, one right after the other. Knee is healing nicely, started loosing weight (15 pounds in 2 months, 50 to go), I have more energy, and feel more motivated. Yuo've already got the right attitude and all the moral support you could want. We're with you, bud!

[Knight_Errant]

Just to say, the man still rules...

[AsSaSiN]

You the man, get well soon matey. We are all here for you

[YODA]

Thanks guys - it's slow going but this old dog ain't lying down just yet :D

[Andy Gibney]

Flippin 'eck Dave. Thought I'd come back to a healthy Yoda. You do understand that you're supposed to take on his wisdom, not his physique, don't you?

Be wise like me. Stay away from the heavy duty grappling. It's not good for you.

Best you mate. Enjoy your convalesence. Girls will be happy to see more of their Dad again.

Andy

[KickChick]

I was a bit worried there for a (brief) sec ;) ...

Andy, I do believe Yoda has finished convalesing ... (well, at least he should be)

This thread was from 2003 :)

Yoda... you're not lying down are you? ;)

[Richdog]

Sounds like an excuse for being lazy to me. Busted hip? At least think of an excuse a bit more original... :rolleyes:














On a serious note, that must have been a blow, 6-8 weeks minimum is long enough to go clinically insane when you're not doing anything. Time to re-visit some old hobbies maybe? I hope it heals sooner rather than later...:(

[Ad McG]

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